Journal: Frontiers in Molecular Biosciences
Article Title: Lipopolysaccharide Alters the m6A Epitranscriptomic Tagging of RNAs in Cardiac Tissue
doi: 10.3389/fmolb.2021.670160
Figure Lengend Snippet: M 6 A modification profiles of lncRNA& mRNA in LPS and control group. (A) Volcano plots showing the lncRNAs that were differentially methylated between LPS and control group with statistical significance. (B) Volcano plots showing the mRNAs that were differentially methylated between LPS and control group with statistical significance (fold changes ≥1.5 and p < 0.05). (C) Hierarchical clustering analysis the differentially methylated lncRNAs. (D) Hierarchical clustering analysis the differentially methylated mRNAs. Ctrl, control; LPS, lipopolysaccharide.
Article Snippet: Probes specific for 27,770 mRNAs and 10,582 lncRNAs were used to analyze the samples from the LPS and control groups using an m 6 A mRNA and lncRNA Arraystar epitranscriptomic microarray.
Techniques: Modification, Control, Methylation